Diffuse Brainstem Glioma Tumour Study: developing new treatment strategies for Diffuse Pontine Glioma

Not Applicable

Recruiting

• Conditions: Diffuse Pontine Glioma; Diffuse Midline Glioma; High grade glioma; Cancer - Brain

• Registration Number: ACTRN12612001183875
• Lead Sponsor: Dr. David Ziegler

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-11-07
• Last Update Posted: 9 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

1. Patients of any age with clinical and radiological diagnosis of diffuse brainstem glioma
OR
2. Patients with diffuse midline gliomas not involving the brainstem
OR
3. Patients with high grade gliomas in other locations
4. Patients with other histologies may be included only after discussion with the study chair

Exclusion Criteria

1. Patients with low grade gliomas

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
develop new treatment strategies for diffuse pontine glioma by culturing cells from autopsy specimens in vivo and identifying cells/molecules that inhibit the propagation of diffuse pontine glioma[ at the end of study];harvest diffuse pontine glioma specimens, grow viable stem cells and culture new cell lines[ at the end of the study]

Secondary Outcome Measures

Name	Time	Method
il[ Nil]