the Use of 18F-FDG, 18F-DOPA and 68Ga-DOTATATE PET/CT in Patients With NETs That Are Potential Candidates for PRRT
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Number of participants with no response to Peptide Receptor Radionuclide Therapy (PRRT) treatment
研究概览
简要总结
the investigators will follow up after patients with neuroendocrine tumors who undergo PRRT treatment and evaluate the response for treatment using PET/CT with different tracers
详细描述
patients with suspected or biopsy proven NET will undergo imaging using a Combination of 18F- FDG , 18F-DOPA and 68Ga-DOTATATE PET/CT before the stat of PRRT . after two cycles of treatment another two PET/CT are done using 18F- FDG and 18F-DOPA and about 6-8 weeks from last treatment the patient will undergo PET/CT using 18F-DOPA .
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patient with neuroendocrine tumor
- •eligible for PRRT
排除标准
- •younger than 18 years old
- •pregnancy
结局指标
主要结局
Number of participants with no response to Peptide Receptor Radionuclide Therapy (PRRT) treatment
时间窗: 7 months
patients who have no clinical and radiological improvement or worsening in clinical condition or radiologic findings (RECIST )
Number of participants with good response to Peptide Receptor Radionuclide Therapy (PRRT)
时间窗: 7 months
patients who have clinical and radiological improvement (using RECIST CRITERIA )
次要结局
未报告次要终点
研究者
Dr. Nayruz Knaana
Dr.
Sheba Medical Center