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Clinical Trials/NCT05015101
NCT05015101
Completed
N/A

Evaluation of the Clinical and Radiological Outcome of Uncemented Femoral Stems According to Their Proximal Coating.

GCS Ramsay Santé pour l'Enseignement et la Recherche1 site in 1 country408 target enrollmentSeptember 30, 2021
ConditionsArthroplasty

Overview

Phase
N/A
Intervention
Not specified
Conditions
Arthroplasty
Sponsor
GCS Ramsay Santé pour l'Enseignement et la Recherche
Enrollment
408
Locations
1
Primary Endpoint
Engh and Massin Score
Status
Completed
Last Updated
last year

Overview

Brief Summary

Evaluation of the clinical and radiological outcome of uncemented femoral stems according to their proximal coating.

Retrospective study

Detailed Description

On a large population of patients having undergone total hip arthroplasty, divided into two cohorts constituted according to the type of femoral stem implanted (with or without proximal coating by MectaGrip): Primary objective: To compare between the two groups the radiological osseointegration of the stems five years after arthroplasty. Secondary objectives: To compare between the groups * The functional outcome of the arthroplasty * The frequency of radiological abnormalities (stress shielding, osteolysis, periprosthetic fractures or cracks, periprosthetic ossifications) * Frequency of complications

Registry
clinicaltrials.gov
Start Date
September 30, 2021
End Date
December 26, 2021
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
GCS Ramsay Santé pour l'Enseignement et la Recherche
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient aged 18 years or older, having been informed of the research
  • A patient with at least five years of uncemented total hip replacement implanted as a first-line procedure
  • A patient who has been regularly monitored since surgery and for whom all clinical and radiological data are available at the five-year follow-up visit

Exclusion Criteria

  • Patient operated for revision
  • History of femoral fracture (pre or per operative)
  • Chronic treatment likely to affect calcium metabolism and ossification
  • Patient under legal protection, guardianship or curatorship
  • A patient who has indicated his or her opposition to the use of his or her medical data (by completing and returning the non-opposition form that will be sent to him or her).

Outcomes

Primary Outcomes

Engh and Massin Score

Time Frame: 5 years

The osseointegration of each stem will be assessed by the Engh and Massin score which evaluates the fixation (bone margins and bridges) and the stability of the stem (margins, pedestal, remodelling of the calcar, deterioration of the prosthesis-bone interface, migration, and particles) by associating negative or positive values for each of the parameters. The total constitutes an anatomopathological diagnosis of "confirmed bone rehab" (+ 10 pts and more), suspected (between 0 and + 10 pts), "fibrous encapsulation" (between - 10 and 0 pts) or an "unstable" prosthesis (below - 10 pts).

Secondary Outcomes

  • Stability of the femoral stem: axial migration (sinking)(5 years)
  • Stability of the femoral stem: frontal migration (varisation)(5 years)
  • Gruen's zones assessment(5 years)
  • Forgotten Joint Score(5 years)
  • Life span of prostheses(5 years)
  • Oxford hip score(5 years)
  • Periprosthetic ossifications (Brooker classification)(5 years)
  • Periprosthetic fractures (Vancouver classification)(5 years)
  • Harris Hip Score (HHS)(5 years)

Study Sites (1)

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