NCT01679769已完成不适用
Prospective Study In Noninvasive Evaluation of Hepatic Fibrosis in Chronic
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 818
- 试验地点
- 1
- 主要终点
- Evaluation of staging fibrosis with a combination of non-invasive parameters compared to liver biopsy
研究概览
简要总结
The aim of our study is to evaluate liver fibrosis using biochemical markers, FibroScan, and radiology methods in patients with chronic hepatitis B in mainland China.
详细描述
Up to Nov, 2015, total of 818 patients with chronic HBV infection had been enrolled in the study. Paired blood and liver biopsy specimen had been collected. The serum samples stored at -80 degree Celsius. All the liver biopsy samples were judged by three pathology experts, according to Ishak standard.
研究设计
- 研究类型
- Observational
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •clinical diagnosis of chronic hepatitis B or compensated cirrhosis due to chronic hepatitis B virus infection
- •agree to have liver biopsy
排除标准
- •clinical diagnosis of decompensated cirrhosis due to hepatitis B virus or inactive carrier
- •liver diseases due to other origin
结局指标
主要结局
Evaluation of staging fibrosis with a combination of non-invasive parameters compared to liver biopsy
时间窗: within two weeks after liver biopsy
次要结局
- Evaluation of staging inflammation with a combination of non-invasive parameters compared to liver biopsy(within two weeks after liver biopsy)
研究者
Guiqiang Wang
Professor
Peking University First Hospital
研究点 (1)
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