Efficacy of automatic oxygen control with non-invasive ventilation therapy in adults with resting hypoxaemia: A randomised cross-over trial

Not Applicable

Completed

• Conditions: Chronic respiratory disease with resting hypoxaemia; Cardiovascular disease with resting hypoxia; Respiratory - Other respiratory disorders / diseases; Respiratory - Chronic obstructive pulmonary disease; Cardiovascular - Other cardiovascular diseases

• Registration Number: ACTRN12622000132741
• Lead Sponsor: Medical Research Institute of New Zealand (MRINZ)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-01-27
• Study Completion: 2022-07-27
• Last Update Posted: 20 November 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

a) A doctor’s diagnosis of a chronic respiratory and/or cardiovascular disease
b) Oxygen saturation measured by pulse oximetry (SpO2) of less than or equal to 90% while breathing room air

Exclusion Criteria

•Age < 18 years
•Evidence of respiratory infection or colonization with multidrug resistant bacteria, Pseudomonas species, Burkholderia Cepacia or mycobacteria
•Risk of barotrauma, as assessed by the investigator
•Nasal or facial conditions precluding use of NHF or NIV
•Intracranial trauma or trans-nasal neurosurgery (within 6 weeks)
•Any other condition which, at the investigator’s discretion, is believed may present a safety risk or impact the feasibility of the study or the study results

Study & Design

• Study Type: Interventional
• Study Design: Not specified