Arterial oxygenation targets in Intensive Care patients
Recruiting
- Conditions
- Intensive Care patientsMechanical ventilationOxygenation targets
- Registration Number
- NL-OMON19970
- Lead Sponsor
- eiden University Medical Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 1512
Inclusion Criteria
Age ≥ 18 years
Admission to an ICU participating in this study Need for intubation and mechanical ventilation
Exclusion Criteria
Readmitted to the intensive care unit and prior ICONIC inclusion
Invasive ventilation longer than 12 hours directly preceding admission
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All-cause mortality on day 28 after randomisation
- Secondary Outcome Measures
Name Time Method The number of days alive and free from ventilation at day 28 after admission to the intensive care unit (ventilator-free days), <br /><br>ICU-mortality and in-hospital mortality<br /><br>ICU length of stay (LOS), hospital LOS<br /><br>Organ failure (daily)<br /><br>Reintubation rate<br /><br>Cost of hospitalization<br /><br>Ischemic events; myocardial, intestinal, cerebral or peripheral<br /><br>Delirium<br /><br>Blood stream infection and respiratory tract infection<br /><br>Surgical site infection<br /><br>Re-admission within 28 days<br /><br /><br><br>Long term follow-up:<br /><br>Quality of life at 6 and 12 months after randomisation<br /><br>Patient opinion of research and consent in the emergency setting at 6 months after randomisation <br>