EFFECT OF CD8+ T CELL ACTIVATION ON LIVE ATTENUATED HEPATITIS A VACCINE IN OBESITY/OVERWEIGHT CHILDREN AND YOUNG ADULTS

Phase 1

Active, not recruiting

• Conditions: ObesityOverweightNormal weightChildren; Lived attenuated hepatitis A vaccine; CD8 T cell; IFN gamma; Obesity

• Registration Number: TCTR20210825005
• Lead Sponsor: Ratchaphisek Sompoch Grant

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-25
• Study Completion: 2021-09-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Children/adolescent aged 6-25 years old who visit at King Chulalongkorn Memorial Hospital (OPD, annual medical check-up, IPD), and volunteer students who has met WHO obesity criteria

Exclusion Criteria

- Children/young child/adolescent who received Hepatitis A vaccine
- Children/young child/adolescent who has an immunodeficiency or taking any immunosuppressive medication

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IFN gamma-CD3 T cell-CD8 T cell 8 weeks ELISPOT

Secondary Outcome Measures

Name	Time	Method
Granzyme B 8 weeks Flow cytomtrey