A Prospective Trial to Study Whether Functional Magnetic Stimulation Enhances Gastrointestinal Motility in Patients With Chronic Constipation
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Effectiveness of FMS in accelerating the gastric emptying in patients with non-neurological constipation after 5-week conditioning protocol
研究概览
简要总结
The purpose of this study is to evaluate the effects of Functional Magnetic stimulation (FMS) on gastrointestinal motility in patients suffering from chronic constipation due to non-neurological issues.
详细描述
The goal of this pilot study is to evaluate the usefulness of FMS as a noninvasive method to stimulate the GI motility in individuals with non-neurological constipation by adopting a 5-week conditioning protocol performed in a hospital outpatient setting. FMS has demonstrated the ability to generate significant rectal pressure and enhance GI transit in normal and spinal cord injury subjects. With proper abdominal muscle conditioning, FMS may improve colonic motility partly due to improved abdominal muscle tone.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-80
- •constipation defined by the Rome II criteria
排除标准
- •Past history of abdominal surgery
- •past history of diabetes mellitus
- •past history of hypothyroidism
- •past history of inflammatory bowel disease
- •past history of significant psychiatric disturbances
- •past history of drug abuse
- •past history of cardiac pacemakers
- •past history of metal implants
- •patients who cannot travel to keep the follow up
- •patients who are prisoners
- •patients who are mentally handicapped
- •patients who are pregnant
结局指标
主要结局
Effectiveness of FMS in accelerating the gastric emptying in patients with non-neurological constipation after 5-week conditioning protocol
时间窗: 5 weeks after conditioning
次要结局
- Effectiveness of FMS in reducing the colonic transit time in patients with non-neurological constipation after a 5 week conditioning period(5 weeks after conditioning)