Relationship Between Right Ventricular Free Wall Longitudinal Strain and Stroke Volume Index by Thermodilution in Patients Undergoing Cardiac Surgery
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Right Ventricular Dysfunction
- Sponsor
- Tufts Medical Center
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Change of right ventricular function during CABG assessed by right heart strain (%)
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Patients undergoing coronary artery bypass grafting up tp 30% will develop postoperative right ventricle dysfunction. Its imperative for the physician to fully understand the severity of this complication in order to perform an early diagnosis and carry out the appropriate treatment.
Aim:
Investigate the correlation between echocardiographic measurements and hemodynamic changes at different time points in patients undergoing coronary artery bypass graft surgery
Hypothesis:
- Weak correlation between echocardiographic measurements and hemodynamic changes during coronary artery bypass graft surgery
- Echocardiographic measurements would change across different time points during surgery independent of hemodynamic values.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Elective coronary artery bypass graft patients who require pulmonary catheter placement for intraoperative monitoring.
Exclusion Criteria
- •Patients with contraindication to Swan-Ganz catheter placement,
- •Pre-existing atrial arrhythmias,
- •Patients with moderate and/or severe mitral/tricuspid valve stenosis or regurgitation
- •Patients with contraindication to transesophageal echocardiogram probe placement (i.e. esophageal stenosis).
Outcomes
Primary Outcomes
Change of right ventricular function during CABG assessed by right heart strain (%)
Time Frame: during CABG surgery
Assessing the change of RV function during CABG surgery using right heart strain as a percentage of change between RV shortening and RV end diastolic length.
Change of right ventricular function during CABG assessed by stroke volume index (mL/m2)
Time Frame: during CABG surgery
Assessing the change of RV function during CABG surgery using stroke volume index. Stroke volume index measurement as millilitres per square meter (ml/m2)
Secondary Outcomes
- Change in cardiac output measured with Swan-Ganz during CABG(during CABG surgery)