Investigation of the Efficacy of Transversus Thoracic Muscle Plane Block in Patients Undergoing Coronary Artery Bypass Graft Surgery
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- Numeric Rating Scale (NRS) at rest
研究概览
简要总结
In this prospective and controlled study, the investigators investigated the effect of transversus thoracic muscle plane block (TTMP) on analgesia in patients who undergo coronary artery bypass graft (CABG) surgery with median sternotomy. For this purpose, the investigators aimed to compare the hemodynamic responses to surgical incision and sternotomy and, pain intensity, total analgesic consumption, additional analgesic requirements of the patients in the first 24 hours after extubation under postoperative patient-controlled analgesia (PCA) adminisration.
详细描述
Forty-six patients aged 18-70 years, ASA class I-III, who undergo CABG surgery were included in our study. The patients were randomized into the TTKPB group and the control group. Heart rate (HR) and mean arterial pressure (MAP) were recorded before peroperative induction, before skin incision, after skin incision, before sternotomy and after sternotomy. PCA with tramadol was applied after extubation and "Numeric rating scale" NRS scores, total tramadol consumption, number of requests and additional analgesic requirements were recorded at 0, 1, 2, 4, 8, 12 and 24 hours.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA (American Society of Anesthesiologists) classification I-III
- •Coronary artery bypass graft operation with median sternotomy under elective conditions
排除标准
- •Refusing to participate in the study
- •Under 18 and over 70
- •ASA class IV and above
- •EF (Ejection Fraction) < 40%
- •Emergency surgery or reoperation
- •Intraaortic balloon pump placement
- •Known allergy to local anesthetics
- •Coagulation disorder
- •Infection at the block site
- •History of sternotomy
- •Those with chronic pain complaints and long-term use of analgesics
- •Patients who could not be extubated within 12 hours after the operation
研究组 & 干预措施
Transversus Thoracic Muscle Plane Block Group
Transversus thoracic muscle plane block is a single-shot nerve block technique that provides analgesia for the anterior chest wall
干预措施: Transversus Thoracic Muscle Plane Block (Procedure)
Transversus Thoracic Muscle Plane Block Group
Transversus thoracic muscle plane block is a single-shot nerve block technique that provides analgesia for the anterior chest wall
干预措施: Tramadol (Drug)
Control Group
干预措施: Tramadol (Drug)
结局指标
主要结局
Numeric Rating Scale (NRS) at rest
时间窗: Postoperative 24 hours
Numeric Rating Scale (NRS) for postoperative pain
Numeric Rating Scale (NRS) during coughing
时间窗: Postoperative 24 hours
Numeric Rating Scale (NRS) for postoperative pain
Mean arterial pressure
时间窗: Peroperative
Peroperative induction, before skin incision, after skin incision, before sternotomy and after sternotomy.
Heart rate
时间窗: Peroperative
Peroperative induction, before skin incision, after skin incision, before sternotomy and after sternotomy.
Bispectral Index (BIS)
时间窗: Peroperative
Peroperative induction, before skin incision, after skin incision, before sternotomy and after sternotomy.
次要结局
未报告次要终点
研究者
Bensu Tavelli
Principal Investigator
Istanbul University - Cerrahpasa (IUC)