What happens to low doses of aspirin (75 and 150 mg) and how it affects certain blood particles in pregnant women at risk of pre-eclampsia?

Not Applicable

Completed

• Conditions: Pre-eclampsia; Pregnancy and Childbirth

• Registration Number: ISRCTN14693054
• Lead Sponsor: ewcastle upon Tyne Hospitals NHS Foundation Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-03-09
• Study Completion: 2022-03-31
• Last Update Posted: 18 July 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 16

Inclusion Criteria

1. Pregnant women at risk of pre-eclampsia according to NICE criteria

Exclusion Criteria

1. Hypersensitivity to aspirin, salicylic acid compounds, or prostaglandin synthase inhibitors (e.g. certain asthma patients who may suffer an attack or faint)
2. Active, or history of, recurrent peptic ulcer and/or gastric/intestinal haemorrhage, or other kinds of bleeding such as cerebrovascular haemorrhage
3. Haemorrhagic diathesis or coagulation disorders such as hemophilia and thrombocytopenia
4. Severe hepatic or renal impairment
5. Gout
6. Taken aspirin over the preceding 4 weeks
7. Current anticoagulant therapy
8. Unable to give informed consent
9. Multiple pregnancy
10. Known fetal anomaly
11. Vegetarian/vegan diet

Study & Design

• Study Type: Interventional
• Study Design: Not specified