CTRI/2024/06/068425尚未招募Unknown
Association of Interleukin-35 levels in gingival crevicular fluid in periodontal health and disease: A comparative study
Radhika Singh1 个研究点 分布在 1 个国家目标入组 66 人开始时间: 2024年6月15日最近更新:
试验速览
- 阶段
- Unknown
- 状态
- 尚未招募
- 发起方
- 入组人数
- 66
- 试验地点
- 1
- 主要终点
- EFFECT OF NON-SURGICAL PERIODONTAL THERAPY ON IL-35 INCREASED OR DECREASED IN CHRONIC PERIODONTITIS
研究概览
简要总结
Periodontitis is a multifaceted disease involving soft and hard tissues of the oral cavity. The sole reason of periodontitis is the interaction between host tissue and bacteria attached to the teeth forming a biofilm.This study will be conducted to estimate and compare the levels of Interleukin-35 in Gingival crevicular fluid among gingivitis and chronic periodontitis patients before and after non-surgical periodontal therapy and to explore the possibility of using IL-35 as a biomarker for periodontal disease activity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 25.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Subjects with age group between 25-60 years 2.Diagnosis of periodontal disease that is chronic periodontitis with probing pocket depth greater than 3 mm and Clinical attachment loss greater than 3 mm 3.Gingivitis that is patients showing clinical evidence of gingival inflammation but no CAL PPD of less than 3 mm and Gingival index score greater than 1
- •Periodontally healthy individuals that is showing no sign of clinical inflammation and periodontitis.
排除标准
- •1.Systemic illnesses affecting periodontal disease.
- •2.Alcohol and tobacco consumers (in whatever form).
- •3.Females- pregnant or nursing.
- •4.Patient who has undergone periodontal treatment in six months back.
结局指标
主要结局
EFFECT OF NON-SURGICAL PERIODONTAL THERAPY ON IL-35 INCREASED OR DECREASED IN CHRONIC PERIODONTITIS
时间窗: 0 DAYS AND 3 MONTHS
次要结局
- To explore the possibility of using IL-35 as a biomarker for periodontal disease activity.(3 MONTHS 0 DAYS)
研究者
Radhika Singh
Institute of dental sciences pilibhit byepass road Bareilly Uttar pradesh
研究点 (1)
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