A randomised trial to compare two solutions â?? HTK[Histidine-Tryptophan-Ketoglutarate] solution and IGL-1[Institut of georges Lopez-1] solution in perfusing Liver Donor Grafts during cold preservation and bench work[preparing grafts before transplant] during Living Donor Liver Transplantatio
Phase 1
- Conditions
- Health Condition 1: K746- Other and unspecified cirrhosis ofliver
- Registration Number
- CTRI/2020/03/023883
- Lead Sponsor
- AMRITA INSTUTE OF MEDICAL SCIENCES
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All adult patients undergoing Living Donor Liver Transplantation in Amrita Institute of Medical Sciences
Exclusion Criteria
APOLT
ABO incompatible transplants
Pediatric transplants
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Early allograft dysfunction [Day 7 Bilirubin greater than 10, Day 7 INR greater than 1.6, Peak SGOT/PT greater than 2000]Timepoint: First week after surgery
- Secondary Outcome Measures
Name Time Method 90 day mortalityTimepoint: 6 months after surgery;Acute Cellular RejectionTimepoint: 6 months after surgery;Bile leak, Biliary strictureTimepoint: 6 months after surgery;Hepatic artery thrombosisTimepoint: 6 months after surgery