The effect of simvastatin on the mortality of sepsis patients
Not Applicable
- Conditions
- Sepsis.Sepsis unspecified
- Registration Number
- IRCT2015111118543N2
- Lead Sponsor
- ?Vice chancellor for research and technology, Shahid Sadoughi University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
all adult patients admitted to ICU with sepsis
Exclusion criteria: Pregnancy, cirrhosis, level of AST and ALT > 3 times the upper limit of normal, CRP> 3 times the upper limit of normal, consumption of any types of statins 3 weeks before sepsis, sensitivity to statins
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All-cause mortality. Timepoint: Immediately after treatment. Method of measurement: Questionnaire.;APACHE score. Timepoint: Days 1, 3 and 7 after sepsis. Method of measurement: The questionnaire of APACHE II system for classification of disease severity.
- Secondary Outcome Measures
Name Time Method