Clinical Trials for Chronic Urticaria
- Conditions
- chronic urticaria
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Patients aged 20 to 48 years;
2. patients conforming to the diagnostic criteria of refractory chronic urticaria;
3. patients conforming to the diagnostic criteria of TCM wind-heat syndrome;
4. patients having used at least 2 times the conventional dose of antihistamines or at least 2 combined antihistamines with conventional dose for more than 2 weeks;
5. The duration of patients'hives is more than 2 hours;
6. patients able to give stool samples;
7. patients able to sign the informed consent form.
1. Patients dignosed drug-induced urticaria, induced urticaria (cold urticaria, febrile urticaria, cholinergic urticaria), urticaria vasculitis and other skin diseases with urticaria-like manifestations;
2. patients who have been treated well with antihistamines or have been treated with hormones, immunosuppressants, or biological agents, or have received relevant Chinese medicine treatment 1 week before enrollment,or Patients who have received antibiotics and non-steroidal anti-inflammatory drugs 2 weeks before enrollment;
3. patients who are pregnant, or preparing for pregnant, or breastfeeding women;
4. patients suffering serious organic diseases of important organs such as heart, brain, liver and kidney,and those with severe primary diseases of the hematopoietic system, and those with mental illness;
5. patients allergic to the components of Chinese medicine in the research prescription.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method time for hives subsidence;Hive Severity Score;urticaria activity score;Itch Severity Score;
- Secondary Outcome Measures
Name Time Method Sleep disturbance score;Activity Impact Score;Dermatology Life Quality Index;