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Investigating the clinical efficacy and mechanism of Runfei Huayu recipe in treating connective tissue disease merger interstitial lung disease based on Th17/Treg glycolytic pathway

Phase 1
Conditions
Connective tissue disease merger interstitial lung disease
Registration Number
ITMCTR2200006523
Lead Sponsor
Taizhou Hospital of traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Meet the diagnostic criteria of traditional Chinese and western medicine for CTD-ILD;
2. 35 years = age =75 years, male or female;
3. This study was approved by the ethics committee of our hospital, and informed consent was obtained from patients with signed informed consent;
4. No fertility requirement.

Exclusion Criteria

1. Patients with pulmonary tuberculosis, chronic obstructive pulmonary disease, emphysema, bronchiectasis, lung tumors, silicosis, pneumoconiosis and other lung diseases;
2. Patients with some serious primary diseases, such as digestive, respiratory, cardiovascular, hematopoietic and nervous system diseases, mental diseases, etc.;
3. Abnormal liver and kidney function, such as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) exceeding 1.5 times the normal value, blood creatinine (Scr) and urea nitrogen (BUN) any higher than the normal value;
4. Allergic constitution and allergic to clinical study medication;
5. Women who are during pregnancy, preparing for pregnancy, or during breastfeeding period.

Study & Design

Study Type
Observational study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
ung function;Lung CT;
Secondary Outcome Measures
NameTimeMethod
TCM syndrome integral;
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