Evaluation and Compararison of diagnostic and prognostic accuracy of different biomarkers like Procalcitonin, CD64, Group II phospholipase A 2 and Human neutrophil lipocalin for adult sepsis and septic shock in sick patients admitted in Emergency Department.
Phase 4
Not yet recruiting
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2025/06/088741
- Lead Sponsor
- Sanjay Gandhi Post Graduate Institute
- Brief Summary
**Project summary-**
Thoughit’s well known that timely identification of septic shock is decisive toimprove any septic patient’s mortality, no biomarker is still existing todetect it in the initiation. Procalcitonin, CD64,Group II phospholipaseA 2, and Human neutrophil lipocalin are the promising one among 260 tested biomarkers.In our study, we want to compare the diagnostic accuracy of these biomarkers inseptic shock patients in our emergency department. Additionally, prognosticguidance if any will be seen.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 118
Inclusion Criteria
- 1 Age more than 18 years 2.
- sepsis according to sepsis 3 criteria.
- 3, emergency department.
Exclusion Criteria
- Not giving consent for test.
- Patients with immune-related diseases- can influence biomarker level.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The diagnostic accuracy of CD64, PLA 2GIIA, HML and Procalcitonin in sepsis and septic shock patients in emergency department. 1 year
- Secondary Outcome Measures
Name Time Method any correlation between mortality with admission biomarker levels & admission SOFA score. 1 year
Trial Locations
- Locations (1)
Department of Emergency Medicine
🇮🇳Lucknow, UTTAR PRADESH, India
Department of Emergency Medicine🇮🇳Lucknow, UTTAR PRADESH, IndiaTanmoy GhatakPrincipal investigator09455037848tanmoyghatak@gmail.com