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A study of hematologic disorder in chronic obstructive pulmonary disease patients

Completed
Conditions
to study the relationship between hematologic disorders and COPD and to study various factors affecting hematologic disorders.
chronic obstructive pulmonary disease, anemia, polycythemia, hemoglobin
Registration Number
TCTR20210504002
Lead Sponsor
grant from Faculty of Medicine, Srinakharinwirot University (Contract No 155/2563).
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
125
Inclusion Criteria

All chronic obstructive pulmonary disease patients visited to the COPD clinic, HRH Princess Maha Chakri Sirindhorn Medical Center Hospital between January 1, 2016, and December 31, 2019.

Exclusion Criteria

Patients with other lung diseases besides COPD such as asthma, infectious lung diseases, autoimmune diseases, cancer, metabolic diseases, hematologic diseases (leukemia, lymphoma, myeloproliferative disorder, pure red cell aplasia, thalassemia, bone marrow disease Heart failure Ischemic heart disease and osteoporosis
Patients who are treated with antibiotics and/or corticosteroids for a long time including any treatment that causes low immunity
Patients who lack follow-up
Patients with chronic renal disease stage 4 or 5
Patients without complete blood count results
Dementia
The variables used in this study were recorded including gender, age, body mass index(BMI), respiration rate, pulse rate, serum hemoglobin, hematocrit, leukocyte, eosinophil, mean corpuscular volume(MCV), MCHC, platelet, serum albumin, serum cholesterol, creatinine, glomerular filtration rate(GFR), peak expiratory flow rate(PEFR), post-bronchodilator FEV1, 6-minute walking distance, resting O2 saturation, frequency of exacerbations and frequency of admission.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
hematologic disorders data will be collected at the nearest time that COPD is diagnosed. CBC
Secondary Outcome Measures
NameTimeMethod
to study various factors affecting hematologic disorders. data will be collected at the nearest time that COPD is diagnosed. Complete blood count, biochemistry laboratory results, lung function test, 6-minute walking distance, frequency of exacerbations and admission were recorded
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