Bone Mass in Patients with Familial Adenomatous Polyposis

• Conditions: high bone mass; osteopetrosis; 10083624; 10017934; 10017987

• Registration Number: NL-OMON32091
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 25

Inclusion Criteria

- Genetically and histologically documented diagnosis of FAP
- Informed consent

Exclusion Criteria

- Use of bisphosphonates in the last 3 years
- Current use of PTH (1-34 or 1-84)

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The potential effect of genetic abnormalities in the APC gene on bone mineral<br /><br>density in patients with Familial Adenomatous Polyposis (FAP).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The potential effect of genetic abnormalities in the APC gene in FAP patients on<br /><br>- bone and mineral metabolism<br /><br>- prevalence of fractures<br /><br>- prevalence of joint disorders.</p><br>