A study comparing effectiveness of oral methadone and sublingual buprenorphine in controlling symptoms of acute withdrawal in individuals addicted to opioid drugs
- Conditions
- Health Condition 1: null- Patients of opioid dependence syndrome according to ICD- 10 criteria and coming to NDDTC for treatment
- Registration Number
- CTRI/2017/03/007977
- Lead Sponsor
- DDTC AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion criteria for Cases:
Male patients between 18 and 60 years of age
Diagnosis of opioid dependence syndrome according to ICD- 10 criteria
Dependent on Heroin (any route) or Injection Buprenorphine or Injection Pentazocine
Should have taken last dose of any opioid within 48 hrs of admission
Subject willing to give written informed consent
Exclusion criteria for Cases:
Dependence on any other substance except Nicotine
Exposure to either Buprenorphine or Methadone for treatment in preceding 3 months (either detoxification or maintenance)
Admission to any facility within last 3 month
Patients requiring other psychotropic medicines (like Benzodiazepines, TCAs, etc.) which can suppress symptoms of opioid withdrawal except hypnotic purposes
Patients on other medications which can significantly affect serum levels of Buprenorphine or Methadone either prior to admission or during admission
Any known medical contraindication to either medications
Co-morbid psychiatric illness
Patients previously randomized for this study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method