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Comparison of PR Efficiency in Home-based With Hospital-based PR in Bronchiectasis

Not Applicable
Recruiting
Conditions
Bronchiectasis
Lung Diseases
Lung Diseases, Interstitial
Pulmonary Rehabilitation
Interventions
Other: Hospital-based pulmonary rehabilitation
Other: Home-based pulmonary rehabilitation
Registration Number
NCT03561818
Lead Sponsor
Istanbul Medipol University Hospital
Brief Summary

The investigators aimed to compare the home-based Pulmonary Rehabilitation with the hospital-based pulmonary rehabilitation in terms of pulmonary rehabilitation efficiency in patient with bronchiectasis.

Detailed Description

While the benefits of pulmonary rehabilitation (PR) in cases of chronic obstructive pulmonary disease (COPD) have been well-documented, there have been only a limited number of studies investigating the efficacy of PR in patients with bronchiectasis. Some of these studies have reported positive effects of PR also in bronchiectasis patients, but have underlined the need for additional studies including larger patient groups to define PR indications, and to ensure that exercise protocols are specific for this patient group. There are many PR organizational types, such as hospital-based, telephone-mentoring with home-based or tele monitorization programs. Hospital-based supervised programs are time-consuming and costly practices. For this reason, there is a need for further studies on the effectiveness and benefits of unsupervised programs. In this study, we will compare unsupervised home-based PR and supervised hospital-based PR in terms of pulmonary rehabilitation effectiveness.

The pulmonary function tests, dyspnea perception, quality of life and exercise capacity assessments will performed before and after pulmonary rehabilitation.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
50
Inclusion Criteria
  • Between the ages of 18-70
  • Patients signing informed consent form
  • Bronchiectasis patients in the stable phase who were diagnosed with High-resolution computed tomography (HRCT).
Exclusion Criteria
  • Decompensated heart failure, uncontrolled hypertension (Systolic Blood Pressure> 200, Diastolic Blood Pressure> 110),
  • Additional diseases that may prevent exercise,
  • To be regularly exercising regularly

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Hospital-based groupHospital-based pulmonary rehabilitation2 months hospital-based pulmonary rehabilitation program
Home-based groupHome-based pulmonary rehabilitation2 months home-based pulmonary rehabilitation program
Primary Outcome Measures
NameTimeMethod
Changes from baseline the 6-minute walking distance at two months.Two months
Changes from baseline the modified Medical Research Council (mMRC) scale at two months.Two months

Dyspnea perceptions during daily life activities will assess according to the modified Medical Research Council (mMRC) scale. The mMRC Dyspnea Scale is best used to establish baseline functional impairment due to dyspnea attributable to respiratory disease; tracking the mMRC over time or with therapeutic interventions is of less certain clinical utility.The severity of dyspnea is rated on a scale of 0 to 4. "0" means no dyspnea perception, "4" means severe dyspnea perception.

Secondary Outcome Measures
NameTimeMethod
Changes from baseline the peripheral muscle strength at two months.Two months

Peripheral Muscle Strength will measure using a digital dynamometer(J-Tech Commander muscle testing device), with three measurements make in total of the quadriceps femoris, tibialis anterior and iliopsoas muscles.

Changes from baseline the forced expiratory volume in one second at two months.Two months

The Pulmonary Function Test conducted using a Sensor Medics model 2400 device (Yorba Linda, CA, USA), in line with American Thoracic Society (ATS) guidelines.

Changes from baseline the Quality of Life at two months.Two months

St. George Respiratory Questionnaire

Trial Locations

Locations (1)

Yedikule Chest Disease Hospital

🇹🇷

Istanbul, Zeytinburnu, Turkey

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