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Clinical Trials/NCT01945541
NCT01945541
Completed
Not Applicable

Body Composition Monitoring for Determination of the Fluid Status in Patients Undergoing General Anesthesia

Medical University of Vienna1 site in 1 country73 target enrollmentAugust 2013
ConditionsFluid Overload

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fluid Overload
Sponsor
Medical University of Vienna
Enrollment
73
Locations
1
Primary Endpoint
Postoperative overhydration in liter measured by Body Composition Monitor
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The purpose of this study is to evaluate a recently developed device, which measures body composition (i.e. the water content of the body) in the perioperative setting. Specifically the investigators will test the hypothesis, that extracellular water content after surgery correlates to the amount of intraoperative infusion and positive fluid balance. Furthermore the investigators will test, if preoperative evaluation of body water helps to determine intraoperative fluid requirements and to guide fluid administration.

Detailed Description

Patients undergoing anesthesia and surgery receive intravenous fluids during the procedure. The amount of administered fluid depends on the type of surgery, cardiovascular stability and intraoperative losses like hemorrhage. Fluid overload as well as hypohydration might be detrimental and might adversely effect outcome after surgery. Specifically overhydration results in significant weight gain, tissue edema and increased morbidity. Technically assisted assessment of volume status before surgery may be useful to direct intraoperative fluid administration and to prevent postoperative volume overload. As a prerequisite the investigators will test a recently developed whole-body bioimpedance spectroscopy device to determine the pre-to postoperative fluid distribution. This body composition monitor (BCM, Fresenius Medical Care, Germany) separates between extracellular and intracellular fluid volume non-invasively by applying a frequency sweep from 3-1000 kilohertz through the entire patient via electrodes placed on the wrist and ankle. The investigators will test the hypothesis that 1. the amount of administered fluid correlates with the amount of overhydration measured postoperatively. 2. that preoperative BCM measurements and thus information about the preoperative hydration state might help to guide fluidmanagement and to reduce the amount of over/ hypohydration postoperatively.

Registry
clinicaltrials.gov
Start Date
August 2013
End Date
August 24, 2016
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Barbara Kabon

PD. MD.

Medical University of Vienna

Eligibility Criteria

Inclusion Criteria

  • 18-80 Years

Exclusion Criteria

  • liver, heart, kidney failure, patients with pacemaker

Outcomes

Primary Outcomes

Postoperative overhydration in liter measured by Body Composition Monitor

Time Frame: Measurements will be performed immediatley before and after surgery. The expected time frame will thus be 2-4 hours.

Study Sites (1)

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