Body Composition Monitoring(BCM) for Determination of the Fluid Status in Patients Undergoing General Anesthesia

Not Applicable

Completed

• Conditions: Fluid Overload
• Interventions: Device: Body Composition Monitoring

• Registration Number: NCT01945541
• Lead Sponsor: Medical University of Vienna

Brief Summary

The purpose of this study is to evaluate a recently developed device, which measures body composition (i.e. the water content of the body) in the perioperative setting. Specifically the investigators will test the hypothesis, that extracellular water content after surgery correlates to the amount of intraoperative infusion and positive fluid balance. Furthermore the investigators will test, if preoperative evaluation of body water helps to determine intraoperative fluid requirements and to guide fluid administration.

Detailed Description

Patients undergoing anesthesia and surgery receive intravenous fluids during the procedure. The amount of administered fluid depends on the type of surgery, cardiovascular stability and intraoperative losses like hemorrhage. Fluid overload as well as hypohydration might be detrimental and might adversely effect outcome after surgery. Specifically overhydration results in significant weight gain, tissue edema and increased morbidity. Technically assisted assessment of volume status before surgery may be useful to direct intraoperative fluid administration and to prevent postoperative volume overload. As a prerequisite the investigators will test a recently developed whole-body bioimpedance spectroscopy device to determine the pre-to postoperative fluid distribution. This body composition monitor (BCM, Fresenius Medical Care, Germany) separates between extracellular and intracellular fluid volume non-invasively by applying a frequency sweep from 3-1000 kilohertz through the entire patient via electrodes placed on the wrist and ankle.

The investigators will test the hypothesis that

1. the amount of administered fluid correlates with the amount of overhydration measured postoperatively.

2. that preoperative BCM measurements and thus information about the preoperative hydration state might help to guide fluidmanagement and to reduce the amount of over/ hypohydration postoperatively.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2013-08
• Study First Submitted: 2013-08-31
• Study First Submitted QC: 2013-09-14
• Study First Posted: 2013-09-18
• Primary Completion: 2015-06
• Study Completion: 2016-08-24
• Status Verified: 2020-07
• Last Update Submitted: 2020-07-10
• Last Update Posted: 2020-07-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 73

Inclusion Criteria

18-80 Years

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Exclusion Criteria

liver, heart, kidney failure, patients with pacemaker

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
body composition monitoring preoperative	Body Composition Monitoring	pre and postoperative BCM measurements

Primary Outcome Measures

Name	Time	Method
Postoperative overhydration in liter measured by Body Composition Monitor	Measurements will be performed immediatley before and after surgery. The expected time frame will thus be 2-4 hours.

Trial Locations

Locations (1)

Medical University of Vienna; 🇦🇹 Vienna, Austria