La désensibilisation Aux Venins d'hyménoptères : Quelle Est Son efficacité à Long Terme ? (EFLOTITA2)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 290
- 试验地点
- 1
- 主要终点
- Reccurence of a systemic reaction
研究概览
简要总结
Allergy to Hymenoptera venom is one of the main causes of anaphylaxis in adults, and is less common in the paediatric population. It can be severe or even fatal.
Despite the use of an emergency kit, including an adrenaline auto-injector (AAI), at present only hymenoptera venom immunotherapy (VIT) is effective in preventing subsequent severe systemic reactions.
Recurrence during the 5 years following cessation of VIT is about 10-15 percent. Studies evaluating longer-term efficacy are scarce.
At the University Hospital of Angers, hundreds of patients are treated each year, and its allergology unit has been providing VIT for over 15 years.
The purpose of this stufy is to evaluate VIT efficacy among patients who were treated with VIT and ceased VIT from 2005 to 2019, at the university hospital of Angers.
详细描述
Allergy to Hymenoptera venom is one of the main causes of anaphylaxis in adults, and is less common in the paediatric population. It can be severe or even fatal.
Despite the use of an emergency kit, including an adrenaline auto-injector (AAI), at present only hymenoptera venom immunotherapy (VIT) is effective in preventing subsequent severe systemic reactions.
Recurrence during the 5 years following cessation of VIT is about 10-15 percent. Studies evaluating longer-term efficacy are scarce.
At the University Hospital of Angers, hundreds of patients are treated each year, and its allergology unit has been providing VIT for over 15 years.
The purpose of this stufy is to evaluate VIT efficacy among patients who were treated with VIT and ceased VIT from 2005 to 2019, at the university hospital of Angers.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Allergy to hymenoptera venom.
- •Treated with VIT at the university hospital of Angers.
- •Ceased VIT between 2005 and 2019.
排除标准
- •Patient's opposition, or the Participant's legal guardian's, if minor, to participate to the study, and/or for his data to be used.
结局指标
主要结局
Reccurence of a systemic reaction
时间窗: up to 17 years since the patient ceased hymenoptera venom immunotherapy.
The recurrence of a systemic reaction after a hymenoptera sting reported by the patient during the telephone survey.
次要结局
- To describe the evolution of the results of the allergy work-up during hymenoptera venom immunotherapy(up to 17 years since the patient ceased hymenoptera venom immunotherapy to the last appointement in the allergy unit.)
- Predicting the recurrence of systemic symptoms(up to 17 years since the patient ceased hymenoptera venom immunotherapy until the phone survey)