General Anesthesia on Blood Pressure and Intraocular Pressure in Geriatric Patients Undergoing Cataract Surgery

Recruiting

• Conditions: Cataract
• Interventions: Other: Intraocular pressure (IOP) was measured

• Registration Number: NCT06482996
• Lead Sponsor: Umraniye Education and Research Hospital

Brief Summary

The primary aim of the study is to investigate the correlation between preoperative hemodynamics and frailty scores in patients undergoing cataract surgery under general anesthesia. The secondary objective is to explore the relationship between preoperative and postoperative intraocular pressure changes and frailty scores.

Detailed Description

Cataract stands as a significant cause of vision impairment worldwide, notably prevalent among the elderly. This study aims to explore the changes in intraocular pressure (IOP) and blood pressure under general anesthesia during cataract surgery in frail geriatric patients. The research emphasizes the critical role of frailty assessment in determining surgical risks among elderly surgical patients. It focuses on the hypothesis that frail individuals undergoing cataract surgery under general anesthesia might experience more pronounced effects on IOP and blood pressure during the surgical procedure compared to prefrail counterparts. This study emerges as a crucial step in understanding the impact of preoperative frailty assessment on surgical planning and outcomes.

Study Timeline

• Study Start: 2023-10-20
• Study First Submitted: 2024-05-06
• Study First Submitted QC: 2024-06-25
• Study First Posted: 2024-07-01
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-11
• Last Update Posted: 2025-03-12
• Primary Completion: 2025-04-28
• Study Completion: 2025-05-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• 65-85 age
• ASA I-III
• cataract surgery with genel anesthesia

Exclusion Criteria

• cerebrovascular disease,
• mental retardation and psychiatric illness,
• pulmonary infection, history of advanced COPD or respiratory failure,
• EF less than 40%, presence of cardiovascular disease,
• bleeding diathesis,
• renal and hepatic insufficiency,
• presence of diabetes mellitus, diuretic/mannitol users,
• substance abuse
• BMI >30

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
group A	Intraocular pressure (IOP) was measured	Frail scale:Non frail
group B	Intraocular pressure (IOP) was measured	Frail scale: Pre frail/frail

Primary Outcome Measures

Name	Time	Method
intraocular pressure during genel anesthesia	through study completion, an average of 1 day	intraocular pressure (mmHg)

Secondary Outcome Measures

Name	Time	Method
hemodynamic data	through study completion, an average of 1 day	mean arterial pressure (mmHg)

Trial Locations

Locations (1)

Umraniye Education and Research hospital; 🇹🇷 Istanbul, Turkey