Establishment and analysis of a yellow fever vaccination cohort for the identification of individual prognostic factors in vaccinations and acute viral infections

udwig Maximilian University of Munich0 sites250 target enrollmentAugust 26, 2023

Overview

Registry

who.int

Start Date

August 26, 2023

End Date

April 28, 2023

Last Updated

2 years ago

Study Type

Observational

Sex

All

Sponsor

udwig Maximilian University of Munich

•1\. Male or female individuals between the ages of 18 and 55 years old
•2\. Healthy with no acute infections or chronic diseases
•3\. Women must have a negative pregnancy test
•4\. Willingness to provide written informed consent after being thoroughly informed of the risks and benefits of the study
•5\. Availability for all study time points (i.e., able to attend all study visits)

•1\. Pregnant or lactating women
•2\. Previously received a yellow fever vaccination
•3\. Pre\-existing flaviviral diseases such as dengue fever or West e virus infection
•4\. Known allergies to egg or egg components or aminoglycosides
•5\. A temperature greater than 38°C on the day of study entry or an acute illness (with or without fever) on the same day
•6\. Receipt of any other vaccination less than 30 days before the study
•7\. A history of autoimmune diseases or immunosuppression
•8\. Known anaphylactic or allergic reactions
•9\. Using unregistered drugs or drugs in clinical trials
•10\. Clinically significant mental illness