跳至主要内容
临床试验/CTRI/2021/01/030494
CTRI/2021/01/030494招募中不适用

A prospective observational study of preoperative assessment and optimization of high risk surgical patients posted for gastrointestinal cancer surgeries and their perioperative outcomes

Tata Memorial Hospital1 个研究点 分布在 1 个国家目标入组 1,250 人开始时间: 2021年1月2日最近更新:

试验速览

阶段
不适用
状态
招募中
入组人数
1,250
试验地点
1
主要终点
Postoperative complications as per Clavien Dindo class of complications

研究概览

简要总结

The number of patients undergoing surgery and other related invasive interventions has been growing over the years; along with a large population moving into the elderly population. Abdominal surgeries carry high perioperative risks with high risk populations carrying multiple and uncontrolled comorbidities. Periâ€operative medicine is based on improving the care of patients to maximize the quality of life. High-risk surgeries have been defined as those with a mortality of >5%. A number of scoring systems and diagnostic tests have been used to help identify patients and operations with high risk and allow appropriate management to be started early in the perioperative period. The most commonly used systems are the POSSUM score and ASA grading. Perioperative medicine aims include preoperative risk stratification using cardiopulmonary exercise testing for patients undergoing major abdominal surgery, preoperative management of iron deficiency and anemia, and preoperative exercise intervention.

Proof of the utilization and validity for improving surgical outcomes with such tools in preoperative care is still not well established and evidence-based developments in this field will likely be beneficial to patients undergoing major abdominal surgery, but further research into such fields is required.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 90.00 Year(s)(—)
性别
All

入选标准

  • Gastro-intestinal cancers with American society of anesthesiologist class 1-4, having high risk (surgical or anaesthesia risk) and who are planned to be assessed in preoperative high risk joint clinic.

排除标准

  • Emergency Surgery.

结局指标

主要结局

Postoperative complications as per Clavien Dindo class of complications

时间窗: From day of surgery to 30 days postoperatively

次要结局

  • Need for postoperative ventilation, number of days of ventilation, number of days in ICU,number of stay in hospital, Re-admission in ICU and readmission in hospital and 30 days’all-cause mortality.(From day of surgery to 30 days postoperatively)

研究者

申办方类型
Research institution and hospital

研究点 (1)

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