Burden of Influenza at Emergency Department Level : BIED

Not Applicable

Completed

• Conditions: Emergencies; Flu
• Interventions: Other: Nasal swab

• Registration Number: NCT04153331
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Seasonal influenza surveillance in France relies on several sources to detect the onset of the epidemic early, as well as to estimate the severity of epidemics and their impact on the health system. However, the data collected do not fully measure the impact of epidemics on the hospital system.

Increasing the investigator's knowledge of the impact of influenza on the hospital system, particularly on emergencies, which are the most affected service, is essential to better adapt the resources put in place to care for patients.

The study will allow a better understanding of the influenza burden, by systematically documenting the severe events (i.e. requiring consultations to the Emergency Rooms) that are triggered by influenza but not necessarily reported/recorded as influenza.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-11-04
• Study First Submitted QC: 2019-11-05
• Study First Posted: 2019-11-06
• Status Verified: 2020-01
• Study Start: 2020-01-13
• Primary Completion: 2020-03-09
• Study Completion: 2020-03-09
• Last Update Submitted: 2020-05-29
• Last Update Posted: 2020-06-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2487

Inclusion Criteria

• Age > 18 years
• Consultation for a medical cause

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Exclusion Criteria

• Consultation for a non-medical cause (trauma...)
• Pregnant, parturient and lactating women
• Persons deprived of their liberty
• Persons of full age who are subject to a legal protection measure
• Persons not affiliated to a social security system

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Patients admitted to emergency department with medical cause	Nasal swab	Patient included in emergency with a nasal swab

Primary Outcome Measures

Name	Time	Method
Proportion of laboratory confirmed influenza among patients admitted to Emergency Room during the influenza season	1 day (at admission)	The proportion of laboratory confirmed influenza cases will be calculated by dividing the number of patients with laboratory confirmed influenza by the total number of patients included

Secondary Outcome Measures

Name	Time	Method
Proportion of patients with co-morbidities	1 day (at admission)	to evaluate the proportion of patients consulting emergency department who have co-morbidities according to the result of the virological sampling
Proportion of patients with laboratory confirmed influenza and related outcomes	1 day (at admission)	to estimate the proportion of patients with a laboratory confirmed influenza stratified on the emergency department visit outcomes (hospitalization in medicine, hospitalization in intensive care unit or return home) and other covariates
Proportion of patients who consult for other causes than influenza	1 day (at admission)	to estimate the proportion of patients with a laboratory confirmed influenza consulting for other causes than influenza
Proportion of asymptomatic influenza cases among patients with laboratory confirmed influenza	1 day (at admission)	The proportion asymptomatic influenza cases will be calculated by dividing the number of patients with asymptomatic influenza by the total number of laboratory confirmed influenza

Trial Locations

Locations (1)

Service Hygiène, Epidémiologie et Prévention; 🇫🇷 Lyon, France