A randomised controlled trial comparing two doses of nebulised dexmedetomidine for suppression of hemodynamic response to laryngoscopy and intubatio
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2021/08/035888
- Lead Sponsor
- no sponsor it is a academic trial
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1)Patients consent.
2)patients who were American Society of Anesthesiologists (ASA) physical status I and II .
3)age between 18 year and 60 years.
4)with normal airway belonging to both the genders undergoing elective surgery under general anaesthesia with endotracheal intubation.
Exclusion Criteria
1)Patients who were not consenting for the study
2)predicted airway difficulty
3)pregnancy
4)renal failure,uncontrolled hypertension, seizure disorders, patient on anti-depressants/anti-psychotics,patients with a poor cardiopulmonary reserve and with body mass index (BMI) >30 kg/m2 were excluded from the study.
5)Patients on beta blockers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the role of nebulised dexmedetomidine dose 1 .5 microgram/kg compared with 1 microgram/kg given pre operatively for attenuation of hemodynamic response to laryngoscopy and intubationTimepoint: baseline, after nebulisation, post induction ,post-intubation at 1min, 5min and 10 min
- Secondary Outcome Measures
Name Time Method to study the dose sparing effect on propofol used during induction.Timepoint: 1 min after intubation