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Clinical Trials/NCT01345604
NCT01345604
Completed
Phase 4

Reducing Posterior Knee Pain Following Total Knee Arthroplasty Using an Intraoperative Posterior Cruciate Ligament (Transcruciate) Injection

University of Saskatchewan1 site in 1 country50 target enrollmentMay 2011

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Arthroplasty, Replacement, Knee
Sponsor
University of Saskatchewan
Enrollment
50
Locations
1
Primary Endpoint
Knee flexion
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

his study is being done because total knee replacements can leave patients with considerable pain after surgery. Therefore, many studies have been done to find the best ways to control knee pain after the surgery. Currently, a popular approach is to use many different techniques to control the pain. This includes injecting freezing (local anesthetic) into the spinal column (spinal anesthetic), injecting freezing close to the nerves of the knee and using various kinds of medications (e.g. narcotics and anti-inflammatory medications). Studies have shown using this a combination of techniques can reduce pain and allow earlier discharge from the hospital. However, one downside to this approach is it does not usually control the pain in the back of the knee. One new technique has been used to try and overcome this. This technique is called a "posterior cruciate ligament block" or "PCL block". It involves injecting a drug into the back of the knee which will block the nerves in this area. Sometimes the investigators refer to this as "freezing".

The purpose of our study is to determine whether this "PCL Block" will improve pain after the total knee replacement surgery. The investigators will also determine whether this technique will improve movement in the knee and lessen narcotic usage after the surgery.

Registry
clinicaltrials.gov
Start Date
May 2011
End Date
May 2013
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Jacelyn Larson

Faculty

University of Saskatchewan

Eligibility Criteria

Inclusion Criteria

  • American Society of Anesthesiologists' (ASA) physical status classification (ASA) I and II patients undergoing unilateral total knee arthroplasty at Saskatoon City Hospital
  • Patients recruited from the practice of 4 orthopedic surgeons

Exclusion Criteria

  • Inability to obtain informed consent
  • Simultaneous bilateral total knee arthroplasty or revision cases
  • Preexisting neurological deficits in the distribution of the femoral nerve or known diagnosis of peripheral neuropathy
  • Coagulopathies
  • Infection either systemically or at the needle insertion sites
  • Allergies to local anesthetics or opioids
  • Patients with a history of narcotic dependency or chronic pain
  • ASA III and IV
  • Body Mass Index (BMI) \> 40

Outcomes

Primary Outcomes

Knee flexion

Time Frame: up to one week postoperative

Secondary Outcomes

  • Postoperative pain score(in PACU , on ward (baseline), and post-op day 1 & 2 at 10am & 6pm)
  • Total narcotic consumption(up to 1 week postoperative)

Study Sites (1)

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