Femoral Block With or Without Ropivacaine for Analgesia After Total Knee Replacement (TKR)

Phase 1

Completed

• Conditions: Total Knee Replacement
• Interventions: Drug: Ropivacaine

• Registration Number: NCT00910013
• Lead Sponsor: Hopital de l'Enfant-Jesus

Brief Summary

Total knee replacement is a painful procedure. Many solutions have been proposed to diminish the post-operative doses of narcotics, including nerve blocks.

The purpose of the study is to compare if the adjunction of intra-articular ropivacaine to a femoral block is more effective on narcotics consumption than the block alone after TKR.

Detailed Description

Not available

Study Timeline

• Study Start: 2006-04
• Primary Completion: 2008-03
• Study Completion: 2008-03
• Status Verified: 2009-05
• Study First Submitted: 2009-05-28
• Study First Submitted QC: 2009-05-28
• Study First Posted: 2009-05-29
• Last Update Submitted: 2011-02-25
• Last Update Posted: 2011-02-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Primary total knee replacement
• Age > 18 years old
• Accept the study

Exclusion Criteria

• Revision surgery
• Use of anticoagulants drugs
• Neurologic disorder
• Unable to sign consent form

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Ropivacaine + femoral block	Ropivacaine	After the surgery is proceeded and after the closure of the joint capsule, 20 cc of ropivacaine 0.5% is inserted intra-articular through a catheter.

Primary Outcome Measures

Name	Time	Method
Narcotic consumption per 24 hours after surgery (mg/kg)	48 hours

Secondary Outcome Measures

Name	Time	Method
VAS score at 24 hours	48 hours

Trial Locations

Locations (1)

CHA-Pavillon Enfant-Jésus; 🇨🇦 Québec, Quebec, Canada