NCT00910013已完成1 期
A Randomized Trial Comparing the Efficacy on Post-operative Analgesia of Intra-articular Ropivacaine Added to a Femoral Block After Total Knee Replacement
Hopital de l'Enfant-Jesus1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2006年4月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Narcotic consumption per 24 hours after surgery (mg/kg)
研究概览
简要总结
Total knee replacement is a painful procedure. Many solutions have been proposed to diminish the post-operative doses of narcotics, including nerve blocks.
The purpose of the study is to compare if the adjunction of intra-articular ropivacaine to a femoral block is more effective on narcotics consumption than the block alone after TKR.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Primary total knee replacement
- •Age > 18 years old
- •Accept the study
排除标准
- •Revision surgery
- •Use of anticoagulants drugs
- •Neurologic disorder
- •Unable to sign consent form
研究组 & 干预措施
Ropivacaine + femoral block
Experimental
After the surgery is proceeded and after the closure of the joint capsule, 20 cc of ropivacaine 0.5% is inserted intra-articular through a catheter.
干预措施: Ropivacaine (Drug)
结局指标
主要结局
Narcotic consumption per 24 hours after surgery (mg/kg)
时间窗: 48 hours
次要结局
- VAS score at 24 hours(48 hours)
研究者
研究点 (1)
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