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Clinical Trials/NCT00910013
NCT00910013
Completed
Phase 1

A Randomized Trial Comparing the Efficacy on Post-operative Analgesia of Intra-articular Ropivacaine Added to a Femoral Block After Total Knee Replacement

Hopital de l'Enfant-Jesus1 site in 1 country80 target enrollmentApril 2006

Overview

Phase
Phase 1
Intervention
Ropivacaine
Conditions
Total Knee Replacement
Sponsor
Hopital de l'Enfant-Jesus
Enrollment
80
Locations
1
Primary Endpoint
Narcotic consumption per 24 hours after surgery (mg/kg)
Status
Completed
Last Updated
15 years ago

Overview

Brief Summary

Total knee replacement is a painful procedure. Many solutions have been proposed to diminish the post-operative doses of narcotics, including nerve blocks.

The purpose of the study is to compare if the adjunction of intra-articular ropivacaine to a femoral block is more effective on narcotics consumption than the block alone after TKR.

Registry
clinicaltrials.gov
Start Date
April 2006
End Date
March 2008
Last Updated
15 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hopital de l'Enfant-Jesus

Eligibility Criteria

Inclusion Criteria

  • Primary total knee replacement
  • Age \> 18 years old
  • Accept the study

Exclusion Criteria

  • Revision surgery
  • Use of anticoagulants drugs
  • Neurologic disorder
  • Unable to sign consent form

Arms & Interventions

Ropivacaine + femoral block

After the surgery is proceeded and after the closure of the joint capsule, 20 cc of ropivacaine 0.5% is inserted intra-articular through a catheter.

Intervention: Ropivacaine

Outcomes

Primary Outcomes

Narcotic consumption per 24 hours after surgery (mg/kg)

Time Frame: 48 hours

Secondary Outcomes

  • VAS score at 24 hours(48 hours)

Study Sites (1)

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