A Comparative Study of the Effect of Chlorhexidine Mouthwash with and without Anti-Discoloration system and Hyaluronic acid on gingivitis and stains
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
研究概览
简要总结
Gingivitis is a reversible inflammatory condition caused by the accumulation of dental biofilm and is characterized by redness swelling and bleeding of the gingiva without loss of periodontal attachment If left untreated it may progress to periodontitis an irreversible condition involving connective tissue destruction loss of periodontal ligament alveolar bone resorption and eventual tooth loss Hence preventing the progression of gingivitis is crucial
Mechanical plaque control remains the gold standard however it requires high patient motivation and manual dexterity Chemical plaque control agents particularly mouthwashes act as useful adjuncts by disrupting biofilm metabolism and reaching areas inaccessible to brushing Chlorhexidine CHX is considered the most effective antiplaque agent due to its strong antimicrobial and anti gingivitis properties though tooth staining is a common side effect To overcome this limitation CHX formulations with an anti discoloration system ADS have been introduced
Hyaluronic acid HA a naturally occurring polysaccharide in periodontal tissues exhibits anti inflammatory bacteriostatic and wound healing properties Its adjunctive use in periodontal therapy has shown promise in reducing gingival inflammation and promoting tissue healing
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Systemically healthy patients both males and females aged 20-50 yrs presenting with gingivitis Subjects who had not received periodontal therapy for the past 3 months Patients who are not smokers Patients who are cooperative and able to come for regular follow up.
排除标准
- •Patients who are not willing to give consent Pregnant and lactating women Subjects with less than 20 permanent teeth remaining Patients using any other supplemental plaque control measures like interdental cleansing aids or mouthwashes Patients who had received either antibiotic or anti inflammatory therapy within three months of baseline examination.
研究者
Rakshitha S
JSS Dental college and Hospital