Effects of circadian misalignment and sleep disturbance on feeding patterns, obesity and the metabolic syndrome
Completed
- Conditions
- obesity overweight10003018
- Registration Number
- NL-OMON34717
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 16
Inclusion Criteria
Subjects have to be in good health, weight stable, non-smokers, not using medication, not have sleep problems, and at most moderate alcohol users. They have to be overweight, BMI 25-29 kg/m2, adolescent and young adult, age 18-30 yrs, men, who are evening people.
Exclusion Criteria
BMI <25 and >30 kg/m2, women, morningpeople, age <18 and >30 year, using any kind of medication, smokers, sleep problems and excessive use of alcohol
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>With the experimental approach the following outcome will appear:<br /><br><br /><br>1) Effects of light- and food-entrained circadian misalignment versus<br /><br>circadian-alignment on:<br /><br>(i) circadian patterns of parameters associated with circadian rhythm, and of<br /><br>parameters associated with food intake patterns, namely patterns of<br /><br>concentrations of the following blood-parameters: melatonin, leptin, glucose,<br /><br>insulin, ghrelin, GLP-1; VAS-ratings on appetite sensations; VAS-ratings on the<br /><br>stress-related POMS- and STAI-questionnaires.<br /><br>(ii) food choice, food reward, and energy intake.<br /><br>(iii) circadian patterns of energy expenditure and its components;<br /><br>(iv) substrate oxidation; macronutrient-balance;<br /><br>(v) circadian patterns of body-temperature;<br /><br>(vi) physical activity and its circadian patterns;<br /><br>(vii) circadian patterns of heart rate<br /><br>viii sleep quality</p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable</p><br>