Prehospital Evaluation and Detection of Induced Coagulopathy in Trauma

• Conditions: TRAUMAINDIZIERTEKOAGULOPATHIE; D65; Disseminated intravascular coagulation [defibrination syndrome]

• Registration Number: DRKS00009559
• Lead Sponsor: Bundeswehrkrankenhaus UlmKlinik für Anästhesie und IntensivmedizinSektion Notfallmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-10-27
• Study Completion: 2018-02-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 148

Inclusion Criteria

patients with a sever mono trauma or a sever multi system trauma

Exclusion Criteria

- sever hypothermia (< 30°C)
- pregnancy
- all types of coagulation inhibitors in patient history expect low dose aspirin
- hereditary or acquired coagulation deficits
- application of tranexamic acid before the blood sample (T0) could be obtained
- patient (or her / his custodian) do not agree to be part of this study

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Do trauma patients with suspected / real blood loss and / or carciocirculatory instability have a TIC already in the prehospital setting (T0 = prehospital setting)?<br>

Secondary Outcome Measures

Name	Time	Method
Secondary Outcome:<br>Do patients with a proven TIC at T0 (longer CFT CFT, lower Clot firmness at T0) need more blood and blood products during their first 24h of treatment (T2 = 24h after injury)<br><br>Tertiary Outcome:<br>Do patients with a proven TIC at T0 (longer CFT CFT, lower Clot firmness at T0) have a higher 28 day mortality (T3 = 28 days after trauma)