EUCTR2014-003733-25-FR进行中（未招募）1 期
Pilot Study related to the effect of clopidogrel on plasmatic soluble CD40 ligand during systemic lupus erythematous - CLOPUS
CHU de BORDEAUX0 个研究点目标入组 30 人开始时间: 2015年6月26日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •- Aged 18-65 years
- •- Diagnosis of SLE according to revised criteria of American College of Rhumatology
- •- Being affiliated to health insurance
- •- Having signed an informed consent (later than the day of inclusion and before any examination required by research)
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 30
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- > 20mg/day of prednisone equivalent for > 7 days 30 days before the pre-inclusion.
- •- Diseases flare 3 months before the inclusion. A disease flare is defined by an increase of SLEDAI score >3 and or a change of the immunosuppressive treatment and or an increase of steroids dose.
- •- Is treated or has received 3 months before the pre-inclusion steroids pulses or intravenous immunoglobulins.
- •- Renal involvement that could required a kidney biopsy.
- •- Required surgery in the next 12 weeks.
- •- Has been treated by cyclophosphamide 3 months before the pre-inclusion.
- •- Has been treated by biotherapy 6 months before the pre-inclusion.
- •- Contraindication to clopidogrel (annex 1).
- •- History of cancer except healed basal cell carcinoma.
- •- History of severe hemorrhage
- •- Disease exposing to hemorrhage
- •- Associated antiphospholipid syndrome
- •- Pregnant or breastfeeding women
- •- No contraception for women of childbearing age
- •- Severe hypertension
- •- Ongoing statin, non-steroidal anti-inflammatory, antiplatelet and anticoagulant drugs.
- •- Being under guardianship
研究者
相似试验
尚未招募
4 期
Does the dual antiplatelet medication of aspirin and either clopidogrel or prasugrel affect inflammatory and oxidative stress measures in individuals with acute coronary syndrome similarly?CTRI/2023/07/055349Pt B D Sharma PGIMS Rohtak
进行中（未招募）
不适用
A double-blind, randomized study of clopidogrel 75 mg/d vs placebo,on a background of ASA 75-100 mg/d,in peripheral arterial disease (PAD) patients receiving a unilateral below knee bypass graft.The CASPAR 2004 study(Clopidogrel and Acetyl salicylic acid in bypass Surgery for Peripheral ARterial disease)Treatment of patients with peripheral arterial disease (PAD),already treated with ASA 75-100 mg/d,receiving a unilateral below knee bypass graft.MedDRA version: 6.1Level: PTClassification code 10003604EUCTR2004-000822-58-ITBRISTOL-M.SQUIBB
进行中（未招募）
不适用
A double blind randomized study of Clopidogrel 75 mg/d versus placebo on a background of ASA 75-100 mg/d, in peripheral disease (PAD) patient receiving a unilateral below knee by-pass graft. - CASPAR 2004MedDRA version: 7.0Level: 1Classification code 10062585EUCTR2004-000822-58-SESanofi-Synthelabo Groupe1,460
进行中（未招募）
1 期
A double blind randomized study of Clopidogrel 75 mg/d versus placebo on a background of ASA 75-100 mg/d, in peripheral arterial disease (PAD) patients receiving a unilateral below knee by-pass graft - CASPAR 2004Peripheral arterial diseaseMedDRA version: 7.0Level: 1Classification code 10062585EUCTR2004-000822-58-FIsanofi-synthelabo groupe1,460
已完成
2 期
The effect of clopidogrel in prevention of access graft thrombosis in upper extremity.Chronic Renal Failure -Hemodialysis.Chronic Renal Failure -DialysisIRCT2013012412256N1Kermanshah Univesity of Medical sciences50