Influence of Two Paraffin Wax Chewing Gums of Different Consistency on the Stimulated Saliva Flow Rate
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 81
- Locations
- 1
- Primary Endpoint
- Stimulated salivary flow rate (ml)
Study Overview
Brief Summary
The study examines two different chewing gums with regard to consistency and its influence on the result of sialometry
Detailed Description
The examination (sialometry) is performed on healthy volunteers. The volunteers must chew on a paraffin gum for seven minutes. After each minute, the amount of secreted saliva is spat into a designated cup and evaluated. This test is performed with Aurosan chewing gum and later with GC Europe chewing gum.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •healthy volunteers
- •non-smoker
- •no medication
Exclusion Criteria
- •physical or mental illnesses
- •regular medication intake
- •pregnant women
- •dementia or persons who are unable to judge or persons with guardianship
- •minor test persons
Arms & Interventions
stimulated salivary flow rate
stimulated salivary flow rate determined in a crossover design: first using Paraffin Pellets from Aurosan GmbH; thereafter using Chewing wax from the Saliva-Check Buffer from GC Europe
Intervention: Paraffin Pellets from Aurosan GmbH (Diagnostic Test)
stimulated salivary flow rate
stimulated salivary flow rate determined in a crossover design: first using Paraffin Pellets from Aurosan GmbH; thereafter using Chewing wax from the Saliva-Check Buffer from GC Europe
Intervention: Chewing wax from the Saliva-Check Buffer from GC Europe (Diagnostic Test)
Outcomes
Primary Outcomes
Stimulated salivary flow rate (ml)
Time Frame: at baseline (approx 40 minutes)
Comparing measurements of stimulated salivary flow rate (ml) after chewing two different chewing gums
Secondary Outcomes
- Change in consistency of chewing gum(at baseline (7 minutes for each chewing gum))