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临床试验/NL-OMON28649
NL-OMON28649已完成不适用

Intravitreal Dexamethason treatment of bacterial endophthalmitis.

Het Oogziekenhuis Rotterdam0 个研究点目标入组 150 人开始时间: 待定最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
150

研究概览

简要总结

indstedt EW, Bennebroek CA, van der Werf DJ, Veckeneer M, Norel AO, Nielsen CC, Wubbels RJ, van Dissel JT, van Meurs JC. A prospective multicenter randomized placebo-controlled trial of dexamethasone as an adjuvant in the treatment of postoperative bacterial endophthalmitis: interim safety analysis of the study drug and analysis of overall treatment results. Graefes Arch Clin Exp Ophthalmol. 2014; 252(10): 1631-1637. Manning S, Ugahary LC, Lindstedt EW, Wubbels RJ, van Dissel JT, Jansen JTG, Gan I, van Goor AT, Bennebroek CA, van der Werf DJ, Ossewaarde-van Norel A, Mayland Nielsen CC, Tilanus M, van den Biesen PR, Schellekens PA, La Heij E, Faridpooya K, van Overdam K, Veckeneer M, van Meurs JC. A prospective multicentre randomized placebo-controlled superiority trial in patients with suspected bacterial endophthalmitis after cataract surgery on the adjuvant use of intravitreal dexamethasone to intravitreal antibiotics. Acta Ophthalmol. 2018; 96(4): 348-355. van Meurs JC, van Dissel JTJ. Another perspective on the treatment of postoperative endophthalmitis: Unclear evidence for the role of vitrectomy. Acta Ophthalmol. 2018; 96(8): e1042-e1043.

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1. Post-cataract bacterial endophthalmitis;
  • 2. Strong, and increasing, irritation of anterior chamber and/or vitreous during postoperative 8 weeks interval.

排除标准

  • Antibiotics treatment.

研究者

发起方
Het Oogziekenhuis Rotterdam

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