Study of immune parameters that may differ between HC and patients with MS : an explorative study

Completed

• Conditions: MS; Multiple Sclerosis; 10003816; 10007951

• Registration Number: NL-OMON37483
• Lead Sponsor: School for Mental Health and Neuroscience

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

Age between 18 and 65
Caucasian offspring

Exclusion Criteria

MS patients: - Non- Caucasian offspring
- Use of immune suppressive medication;Healthy controls: - Non- Caucasian offspring
- Use of immune suppressive or immune modulatory medication
- Having MS or another autoimmune disease

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters include the percentage of suppression of T cell<br /><br>proliferation, the percentage in reduction of either adhesion molecules or<br /><br>migrating immune cells and the secretion of IL-1*. Differences between MS<br /><br>patients and between MS patients and healthy controls will be investigated. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The effects of MS disease activity, type of disease and MS disease medication<br /><br>on functional immune cell characteristics </p><br>