Berlin Registry of Neuroimmunological Entities

Recruiting

• Conditions: ICD-11Codes: 8A40.0; 8A40.2; 8A40.1; 8A40.Y; 8A40.Z; 8A41.1; 8A41.0; 8A41.Z; 8A43.0; 8A43.1

• Registration Number: DRKS00026761
• Lead Sponsor: Charité - Universitätsmedizin Berlin, Experimental and Clinical Research Center (ECRC) AG Klinische Neuroimmunologie

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-11-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 735

Inclusion Criteria

1. MS diagnosis according to current diagnostic criteria (McDonald 2017) or NMOSD or MOGAD diagnosis according to current diagnostic criteria (Wingerchuck 2015) or other autoimmune disease affecting the central nervous system (e.g. radiographic isolated syndrome [RIS], isolated or recurrent optic neuritis, isolated myelitis, autoimmune glial fibrillary acidic protein [GFAP] encephalitis, autoimmune encephalitis, susac-syndrome, Balo's concentric sclerosis) or a self-reported healthy participant. 2. 18 years of age or older 3. able to give written informed consent. 4. proband has health insurance. 5. written consent was given.

Exclusion Criteria

1. contraindication for magnet resonance tomography imaging 2. self-reported pregnancy 3. relevant other disease, which hinders the conduct of the study

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The goal is a comprehensive multimodal characterization of different neuroimmunological disease entities to facilitate diagnostic differentiation between diseases and to identify predictors for the disease course.

Secondary Outcome Measures

Name	Time	Method
structural, functional and patient reported outcome measures