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Feasibility of Music Therapy for Spontaneous Breathing Trials

Not Applicable
Terminated
Conditions
Spontaneous Breathing Trial
Intubation
Mechanical Ventilation
Music Therapy
Interventions
Procedure: Standard care during an SBT
Other: Music therapy plus standard care during an SBT
Registration Number
NCT05008328
Lead Sponsor
Medical University of South Carolina
Brief Summary

In this study, the investigators will study music therapy for patients during breathing trials, a procedure performed in intensive care units. Participants will be assigned either to standard medical care or standard medical care plus music therapy. Participants have a 50/50 chance (like flipping a coin) of being in either group. In the music therapy group, a board-certified music therapist will sing softly with guitar accompaniment to provide music during the breathing trial. The music is in addition to the usual treatment provided by hospital staff. Participants in the standard medical care group will receive the usual medical care given by hospital staff members. Information will be collected from participant's charts and by observation of vital signs during the breathing trial.

Detailed Description

Not available

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
5
Inclusion Criteria
  • Adults 18+
  • Admitted to MUSC's Main Hospital medical intensive care unit (MICU) or Ashley River Tower medical-surgical intensive care unit (MSICU)
  • Intubated and will undergo a spontaneous breathing trial
Exclusion Criteria
  • Patients who have had any prior SBTs
  • Patients known to have a neurological injury
  • Patients who are known to be deaf
  • Patients whom (or whose LAR) are unable or unwilling to give informed consent.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Standard CareStandard care during an SBTStandard hospital care during an SBT.
Music Therapy plus Standard CareMusic therapy plus standard care during an SBTMusic therapy intervention in addition to standard hospital care during an SBT.
Primary Outcome Measures
NameTimeMethod
Proportion of successful initial spontaneous breathing trials (SBTs) vs failed initial SBTsUp to 48 hours after the participant's initial SBT.

A successful SBT is defined as when a patient sustains at least 30 minutes without mechanical ventilator support, as deemed by the respiratory therapist in the participant's chart.

A failed SBT is defined as when a patient requires mechanical ventilator support within 30 minutes of the start of the SBT, as deemed by the respiratory therapist.

Secondary Outcome Measures
NameTimeMethod
Mean minutes sustained off ventilator support for failed SBTsUp to 48 hours after the participant's initial SBT.

Total minutes sustained off ventilator support, as noted by respiratory therapist in the participant's chart.

Mean score of blood pressure at points throughout SBTAt minute 0 of the SBT, 10 minutes into the SBT, and 30 minutes into the SBT

Recording of patient's blood pressure via observation of monitor at three points throughout the SBT

Mean score of heart rate at points throughout SBTAt minute 0 of the SBT, 10 minutes into the SBT, and 30 minutes into the SBT

Recording of patient's heart rate via observation of monitor at three points throughout the SBT

Mean score of respiratory rate at points throughout SBTAt minute 0 of the SBT, 10 minutes into the SBT, and 30 minutes into the SBT

Recording of patient's respiratory rate via observation of monitor at three points throughout the SBT

Mean score of agitation as assessed by the Richmond Agitation-Sedation Scale at points throughout SBTAt minute 0 of the SBT, 10 minutes into the SBT, and 30 minutes into the SBT

* 4 Combative- Overtly combative, violent, immediate danger to staff

* 3 Very agitated- Pulls or removes tube(s) or catheter(s); aggressive

* 2 Agitated- Frequent non-purposeful movement, fights ventilator

* 1 Restless- Anxious but movements not aggressive vigorous 0 Alert and calm

* 1 Drowsy- Not fully alert, but has sustained awakening (eye opening/contact) to voice (\>10 seconds)

* 2 Light sedation- Briefly awakens with eye contact to voice (\<10 seconds)

* 3 Moderate sedation- Movement or eye opening to voice (but no eye contact)

* 4 Deep sedation- No response to voice, but movement or eye opening to physical stimulation

* 5 Unarousable- No response to voice or physical stimulation

Trial Locations

Locations (1)

Medical University of South Carolina

🇺🇸

Charleston, South Carolina, United States

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