Characterization and Evaluation of Diagnostic Biomarkers for Tuberculosis
Completed
- Conditions
- Active Tuberculosis
- Registration Number
- NCT01269268
- Lead Sponsor
- Yonsei University
- Brief Summary
There was no sensitive and specific biomarker for tuberculosis infection, disease progression and predicting the prognosis of treatment. Therefore, the investigators aimed to investigate and evaluate the newer biomarker for the diagnosis of TB infection. To investigate the new biomarker for TB infection, the investigators will recruit the participants including active TB patients, healthy household contacts, healthy community control.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 270
Inclusion Criteria
- active TB patients : diagnosed with active TB through the microbiologic examination, imaging findings
- healthy control : no history of TB treatment, no respiratory symptoms, no evidence of active infectious disease including TB on chest X-ray, no history of close contacts of active pulmonary TB patients
Exclusion Criteria
- pregnant woman
- positive result of human immunodeficiency virus examination
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Characterization of antigens of Mycobacterium tuberculosis K strain for serodiagnosis of tuberculosis 6months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Severance Hospital
🇰🇷Seoul, Korea, Republic of