Gene expression test for diagnosis in tuberculous pleuritis
Not Applicable
- Conditions
- The differential diagnosis between the TB pleuritis and the malignant pleural effusion (MPE) is difficult because the clinical manifestations are the same. the accurate diagnostic test are important.gene expressiontuberculous pleuritismalignant pleural effusion
- Registration Number
- TCTR20190204003
- Lead Sponsor
- Ratchadapiseksompotch Research Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
1. Age not less than 18 year-old
2. The mononuclear cell predominated exudative pleural effusion
3. The subjects display voluntary for thoracocentesis, pleural biopsy and finally receiving the diagnostic result of TB pleuritis (case group) or malignant pleural effusion (control group)
4. The subjects sign consent form before the data collection
Exclusion Criteria
1. The subjects have any contraindication to the invasive procedure, such as bleeding disorder.
2. The polymorphonuclear cell predominated exudative pleural effusion
3. The unknown of the final diagnostic result of pleural effusion
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The level of each gene expression (copies/micro-lite) immediate after enrollment or within 2 weeks if the patient, who diagnosed as the TB pleuritis, rece Droplet digital PCR (copies/micro-lite)
- Secondary Outcome Measures
Name Time Method contraceptive implant removal duration From the start to the end of the procedure Record time in second ,Success rate Immediate after the entire contraceptive rod is removed Success or failure,Satisfaction Immediate after contraceptive implant removal procedure 5 point Likert scale ,Side effect of anesthesia after applying the anesthesia(Ethyl chloride spray or lidocaine Record side effect of anesthesia