Diagnostic Usefulness of Interferon Gamma Release Assay for Active Tuberculosis in Immunocompromised Patients

Completed

• Conditions: Tuberculosis

• Registration Number: NCT00962676
• Lead Sponsor: Yonsei University

Brief Summary

For diagnosis of active tuberculosis, interferon-γ release assay based mycobacterium tuberculosis specific antigen may show higher sensitivity than tuberculin skin test in immunocompromised patients. Therefore, interferon-γ release assay have a role as a rapid diagnostic adjunctive methods for active tuberculosis in immunocompromised patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-07
• Study First Submitted: 2009-08-19
• Study First Submitted QC: 2009-08-19
• Study First Posted: 2009-08-20
• Primary Completion: 2010-12
• Study Completion: 2010-12
• Status Verified: 2012-01
• Last Update Submitted: 2012-01-31
• Last Update Posted: 2012-02-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• Patient suspicious of active tuberculosis with immunocompromised condition

• Immunocompromised condition patients with

  1. solid cancer with chemotherapy
  2. hematologic malignancy
  3. organ transplantation
  4. immunosuppressant
  5. ESRD on renal replacement therapy
  6. diabetes
  7. advanced liver cirrhosis

Exclusion Criteria

• Patients with

  1. less than 20 years
  2. who don't agree the participation of study
  3. hypersensitivity history to tuberculin
  4. pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

Yonsei Univ.; 🇰🇷 Seoul, Korea, Republic of