Monthly Follow up of Interferon Gamma Releasing Assay (IGRA) Among Health-care Workers Treating Tuberculosis (TB) Patients

Completed

• Conditions: Tuberculosis
• Interventions: Other: Blood samplings

• Registration Number: NCT01121068
• Lead Sponsor: Seoul National University Hospital

Brief Summary

Interferon gamma releasing assay(IGRA) is useful to diagnose latent tuberculosis. However,IGRA responses could show within-subject variability. We wanted to determine long-term IGRA variability in health-care workers who continuously expose to tuberculosis patients.

Detailed Description

IGRA will be performed monthly in health-care workers with continuous exposure to tuberculosis patients for 1 year.

Study Timeline

• Study Start: 2010-05
• Study First Submitted: 2010-05-09
• Study First Submitted QC: 2010-05-11
• Study First Posted: 2010-05-12
• Primary Completion: 2011-05
• Study Completion: 2011-12
• Status Verified: 2014-01
• Last Update Submitted: 2014-01-03
• Last Update Posted: 2014-01-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 49

Inclusion Criteria

• Health care workers who are continuously exposed to TB patients Age > 20 years

Exclusion Criteria

• Pregnant Active TB Use of immunosuppressants

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Health care workers	Blood samplings	-

Primary Outcome Measures

Name	Time	Method
Results of interferon-gamma releasing assay	monthly for 1 year

Trial Locations

Locations (1)

Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine and Lung Institute of Medical Research Center, Seoul National University College of Medicine; 🇰🇷 Seoul, Korea, Republic of