Evaluation if weight bearing exercises on patients with knee osteoarthritis treated by stromal cells
Not Applicable
Recruiting
- Conditions
- Knee Osteoarthritis.Osteoarthritis of knee
- Registration Number
- IRCT20180226038870N2
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Knee osteoarthritis of grade 2 or 3 diagnosed by MRI and confirmed by orthopedics surgeon.
Less than one month before enrollment in the present study, the patient underwent intra-knee implantation of bone marrow-derived mesenchymal stromal cells.
Aged between 18-65 years old.
Exclusion Criteria
Uncontrolled medical situations which need frequent medical treatment and therefore patient will be unable regularly participate in follow up sessions of current trial, such as cancers and autoimmune diseases.
Pregnancy and lactating
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Pain on Visual Analogue Scale. Timepoint: Measurement of patients' pain in the knee joint according to Visual Analogue Scale criteria before the intervention and 1 month and 3 months after the intervention. Method of measurement: Pain on Visual Analogue Scale.
- Secondary Outcome Measures
Name Time Method Patients physical function based on Western Ontario and McMaster Universities Osteoarthritis Index. Timepoint: Before intervention and 1 and 3 months after intervention. Method of measurement: Using Western Ontario and McMaster Universities Osteoarthritis Index questionnaire.;Patient walking distance. Timepoint: Before intervention and 1 and 3 months after intervention. Method of measurement: Based on the patient interview.;Standing time. Timepoint: Before intervention and 1 and 3 months after intervention. Method of measurement: Based on the patient interview.;Patient quality of life. Timepoint: Before intervention and 1 and 3 months after intervention. Method of measurement: The 36-Item Short Form Survey (SF-36).