Effect of weight bearing functional exercises and non-weight bearing quadriceps strengthening along with breathing exercises in people with knee osteoarthritis and obesity.

Not Applicable

• Conditions: osteoarthritis.; Osteoarthritis of knee

• Registration Number: IRCT20230427058007N1
• Lead Sponsor: Riphah International University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 August 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

Are aged 40 to 60?years
Both genders
Have had knee pain for 3?months or more
Report a minimum of 3 overall pain severity on 11-point numeric rating scale (NPRS)
Demonstrate tibiofemoral osteophytes on x-ray

Exclusion Criteria

Lateral joint space narrowing greater than or equal to medial joint space narrowing on x-ray according to a radiographic atlas
Knee surgery/joint injection in past 6?months or planned surgery in the next 9?months
Current or past (4?weeks) oral corticosteroids use
Systemic arthritic conditions
Past knee fracture or malignancy
Past hip/knee joint replacement/tibial osteotomy
Unable to walk unaided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain. Timepoint: base line and after 6 weeks. Method of measurement: Numeric Pain Rating Scale.;Functional disability. Timepoint: base line and after 6 weeks. Method of measurement: The Western Ontario and McMaster universities Arthritis Index.;Brain Derived Neurotrophic levels levels. Timepoint: base line and after 6 weeks. Method of measurement: ELISA.;Oxygen saturation. Timepoint: base line and after 6 weeks. Method of measurement: Arterial blood gases.;Stress, Anxiety & Depression. Timepoint: base line and after 6 weeks. Method of measurement: Depression Anxiety and Stress Scale.;HDL and LDL. Timepoint: base line and after 6 weeks. Method of measurement: Lipid profile.