Effect of topical Ropivacaine on extubation response in patients undergoing neurosurgery
Not Applicable
- Conditions
- Health Condition 1: D330- Benign neoplasm of brain, supratentorialHealth Condition 2: C719- Malignant neoplasm of brain, unspecifiedHealth Condition 3: O- Medical and SurgicalHealth Condition 4: O- Medical and Surgical
- Registration Number
- CTRI/2021/12/038820
- Lead Sponsor
- Department of Neuroanesthesiology and Critical care AIIMS New Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients between 18 â?? 65 years of age.
2.ASA grade I & II patients.
3.Patients posted for elective surgergy for
supratentorial tumours
Exclusion Criteria
1.Refusal of consent
2.Patients with history of smoking or
chronic cough
3.Patients with history of upper
respiratory tract infection (URI) in
last 8 weeks
4.Patients with bleeding disorders
5.Previous laryngeal or tracheal surgery
or pathology
6.Patients with history of gastric reflux
7.Patients with preoperative GCS <15
8.Patients with pulmonary disease, renal,
cardiac or hepatic disorders,
uncontrolled diabetes or blood pressure
9.Delayed extubation (more than 1 hr)
10.Patients with BMI > 35kg/mt2
11.Allergy to study drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the incidence of cough between preservative free 0.5% topical ropivacaine and placebo during extubation in patients undergoing supratentorial tumour surgeriesTimepoint: Till 5 minutes after extubation
- Secondary Outcome Measures
Name Time Method 1.To determine the effect of topical ropivacaine on heart rate and blood pressure(SBP,DBP,MAP) changes during emergence in patients undergoing supratentorial tumour surgeries. <br/ ><br>2. To determine the effect of topical ropivacaine on the emergence time, extubation time and recovery time in these patients <br/ ><br>3.To determine the effect of topical ropivacaine on the neurological recovery(modified Aldrete score) and sore throat in the early postoperative period in these patients <br/ ><br> <br/ ><br>Timepoint: <br/ ><br>Till one hour after extubation <br/ ><br>