Effect of exercise in patients with head and neck cancer receiving Chemoradiation therapy.

Recruiting

• Conditions: Head and neck cancer patients receiving chemoradiotherapy

• Registration Number: CTRI/2018/01/011058
• Lead Sponsor: Manipal Academy of Higher Education

Brief Summary

AIM OF THE STUDY: The study aims to compare the effect of aerobic training versus progressive resistance training on functional capacity and quality of life in patients with head and neck cancer receiving chemoradiation therapy.

SIGNIFICANCE OF THE STUDY: This study will help us to ascertain the optimal type of exercise for this patient population.This study will help us to know whether aerobic training or progressive resistance training helps us to improve the functional capacity and quality of life in patients with head and neck cancer.

PROCEDURE:Patients with head and neck cancer receiving chemoradiation therapy will be explained about the study and willing participants will be signing a written informed consent and are screened based on study criteria.Following randomly allocated through computer generated sequence into group A and group B.Group A will receive aerobic training(brisk walking) for 15-20 minutes, 5 days per week for a period of seven weeks.Group B will receive aerobic training 15-20 minutes, 5 days a week ;along with progressive resistance training with resistance band for 10-15 min ,3 days a week for a period of seven weeks.Functional capacity, Quality of life,Fatigue and Skeletal muscle mass are assessed at base line,3 weeks and at 7th week.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-01
• Last Update Posted: 2019-08-01

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Patients with head and neck cancer(STAGE III,IVa AND IVb) receiving chemoradiotherapy with Eastern Cooperative Oncology Group (ECOG) Score <2.

Exclusion Criteria

• 1.Patients with severe Orthopaedic and Neurological problems.
• 2.Inability to comply with study procedures.
• 3.Patients contraindicated to exercise training.
• 4.Platelet Count<30000/ul.
• 5.HB Count< 8 gm/dl.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Functional capacity and Quality of life	baseline,3rd week and 7th week

Secondary Outcome Measures

Name	Time	Method
fatigue and skeletal muscle mass	baseline,3rd week and 7th week

Trial Locations

Locations (1)

KMC Hospital; 🇮🇳 Kannada, KARNATAKA, India

KMC Hospital

🇮🇳Kannada, KARNATAKA, India

TANDRA RACHANA REDDY

Principal investigator

7674022551

rachana2593@gmail.com