Effectiveness of Oral Immunotherapy in patients with allergy to egg white

Not Applicable

Recruiting

• Conditions: Condition 1: IgE-mediated sensitization to Egg white. Condition 2: IgE-mediated sensitization to Egg white.; Anaphylactic reaction due to food; Other adverse food reactions, not elsewhere classified

• Registration Number: IRCT20180116038387N1
• Lead Sponsor: Iran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 March 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 14

Inclusion Criteria

The patients referring to Department of Asthma and Allergy in Rasool Akram Hospital and Jahad Clinic with a history of allergic reaction to egg white up to 2 hours after ingestion and positive Skin Prick test to Egg white
The inability to pass the Oral Food Challenge (OFC) according to the protocol of Middelton Book with using pasteurized raw egg white (Produced by Telavang Egg Industries Co.)

Exclusion Criteria

Age less than 4 years old
History of Cardiovascular diseases
Use of Beta-Blockers and ACE
Severe and Uncontrolled Asthma

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Desensitization. Timepoint: 6 months. Method of measurement: Pass the Oral food challenge test after 6 months use of egg white.;Specific IgE concentration to Egg white. Timepoint: 6 months. Method of measurement: Immunocap.;Specific IgG4 concentration to Egg white. Timepoint: 6 months. Method of measurement: ImmunoCAP.;The size of Skin Prick Test. Timepoint: 6 months. Method of measurement: The size of wheal and Flare(mm).