Analgesic Efficacy of Combined Ultrasound-Guided PECS II and Transeversus Thoracic Plane Blocks Versus Ultrasound-Guided Serratus Anterior Plane Block in Modified Radical Mastectomy: A Prospective Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- The total amount rescue analgesic consumption (morphine) in the first 24 hours postoperatively.
研究概览
简要总结
The aim of this study is to evaluate the analgesic efficacy of combined ultrasound (US)-guided pectoral nerve (PECS) block II and transversus thoracic plane (TTP) block versus US-guided serratus anterior plane (SAP) block in female patients undergoing modified radical mastectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 21 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female patients
- •Aged 21-60 years
- •ASA physical status I, II
- •Scheduled for unilateral modified radical mastectomy
排除标准
- •Patient refusal.
- •Known hypersensitivity to local anesthetics.
- •Body mass index > 35 kg /m
- •Uncooperative or psychiatric patients.
- •Infection at the injection site.
- •Coagulation disorder.
研究组 & 干预措施
Group I (pectoral nerve (PECS) block -transversus thoracic plane (TTP) block group)
Patients will receive unilateral US-guided PECS II block and TTP block on the side of the operation after induction of general anesthesia.
干预措施: Pectoral nerve (PECS) block -transversus thoracic plane (TTP) block (Procedure)
Group II (serratus anterior plane (SAP) block group)
Patients will receive US-guided SAP block after induction of general anesthesia.
干预措施: Serratus anterior plane (SAP) block (Procedure)
结局指标
主要结局
The total amount rescue analgesic consumption (morphine) in the first 24 hours postoperatively.
时间窗: First 24 hours postoperatively.
Rescue analgesia in the form of morphine (3mg IV) will be given if the VAS is ≥ 40, repeated with lock out interval of 5 min guided with the occurrence of complications till the VAS is decreased to less than 40.
次要结局
- The degree of postoperative pain(First 24 hours postoperatively.)
- Intraoperative fentanyl consumption.(Intraoperative)
- Time to first rescue analgesia request.(First 24 hours postoperatively.)
研究者
Alshaimaa Soliman Alasrag
Resident at Anesthesiology, Surgical ICU and Pain medicine
Tanta University