Efficacy and Safety of Pepper seed extract (RPE) and Pepper seed complex extract (RPEC) on reducing body weight and body fat in overweight Female; A 12 week, Randomized, Double-blind, Placebo-Controlled Clinical Trial

Not Applicable

Completed

• Conditions: Endocrine, nutritional and metabolic disease

• Registration Number: KCT0004078
• Lead Sponsor: The Catholic University of Korea, St. Vincent's Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 17 July 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

(1) Adult men and women aged 20 or older and younger than 65 years
(2) Those with a body mass index (BMI) of 23 kg / m2 or more and less than 30 kg / m2
(3) A person who agrees to participate in the Applicable Human Body Examination and who has voluntarily signed a written consent form

Exclusion Criteria

1) Subjects with severe cerebrovascular disease (cerebral infarction, cerebral hemorrhage, etc.), heart disease (angina pectoris, myocardial infarction, heart failure, arrhythmia requiring treatment) within the last 6 months If the subject has a history but is clinically stable, he or she can participate in the test by the examiner's judgment.)
2) Uncontrolled hypertension patients (blood pressure of 160/100 mmHg or more, after 10 minutes of test subjects)
3) Diabetic patients taking fasting blood glucose levels greater than 126 mg / dl, randomized blood glucose levels greater than 200 mg / dl, or taking oral hypoglycemic agents or insulin
4) Persons with TSH of 0.1 µU/ml or greater than 10 µU/ml
5) A person whose creatine is more than twice the normal limit of the testing agency
6) A person whose AST (GOT) or ALT (GPT) is more than three times the normal upper limit of the testing agency
7) A person who complains of severe gastrointestinal symptoms such as heartburn and indigestion.
8) A person who have Allergy in pepper seed
9) A person who believes that the tester is unfit for other reasons

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Body fat rate, body fat amount by DEXA(Dual-energy X-ray absorptiometry)

Secondary Outcome Measures

Name	Time	Method
weight;Waist Circumference, Hip Circumferenc, Waist to Hip Ratio;Body Mass Index(BMI);Visceral Fat Area, Subcutaneous Fat Area, Taoal Fat Area,Visceral fat / Subcutanesou Fat Ratio by CT